Risk Factors for Sepsis in Stroke Patients at Samutprakan Hospital

Abstract

Cerebrovascular disease is a significant concern for hospitals worldwide, including in Thailand. Patients with this condition are at a relatively high risk for infections due to their vulnerability and extended hospital stays. Most deaths occur in hospitals rather than in the community, and infections complicate treatment, increasing the risk of mortality. This study aims to investigate the incidence rate of sepsis and identify associated risk factors in patients with cerebrovascular disease at Samutprakan Hospital.

This retrospective analytical study was conducted at Samutprakan Hospital from April 2018 to April 2022. The study examined sepsis risk factors and incidence rates in patients with cerebrovascular disease. A total of 250 purposive samples were selected. Data collection tools included records with personal information. The data were analyzed using descriptive statistics (means and percentages) and inferential statistics (Chi-square tests).

The study included 250 patients, of which 54.8% were male, with an average age of 65.92 ± 14.87 years. The average length of stay was 18.68 days. The analysis revealed a sepsis rate of 31.2% in patients with cerebrovascular disease. Significant risk factors for sepsis identified were: age: OR 0.81 (95% CI 0.65-1.20, p-value=0.003), alcohol consumption: OR 1.29 (95% CI 1.16-1.43, p-value=0.001), hypertension: OR 0.19 (95% CI 0.10-0.33, p-value=0.000), hyperlipidemia: OR 0.30 (95% CI 0.14-0.62, p-value=0.001), atrial fibrillation: OR 0.23 (95% CI 0.78-0.67, p-value=0.004), malnutrition: OR 4.52 (95% CI 1.96-10.40, p-value=0.000), endotracheal intubation: OR 0.35 (95% CI 0.18-0.67, p-value=0.001).