A Clinical Case Report on Burning Mouth Syndrome Associated with Hypothyroidism
Keywords:
burning mouth syndrome, hypothyroidism, oral diagnosisAbstract
This case report aims to describe the clinical characteristics of a patient with hypothyroidism associated with burning mouth syndrome (BMS), as well as the diagnostic process and management approach. The purpose is to provide clinical insights and reference information for dentists and healthcare professionals in evaluating and managing patients presenting with similar symptoms in the future.
A 62-year-old female patient presented with a burning sensation on the tongue without any visible oral lesions. Laboratory investigations revealed hypothyroidism and anemia, both of which are systemic conditions that may contribute to or exacerbate burning mouth symptoms. The patient was treated with Levothyroxine and vitamin B supplementation, together with oral hygiene modification and behavioral advice.
The patient’s burning sensation decreased from a Visual Analog Scale (VAS) score of 8 to 5 within one month and completely resolved within six months. Follow-up laboratory tests showed normalization of hemoglobin and thyroid hormone levels. This case highlights the importance of accurate diagnosis and individualized treatment planning through multidisciplinary collaboration to ensure comprehensive and etiology-based care. Integrating systemic evaluation with holistic management can effectively reduce symptoms and improve the patient’s quality of life.
Dentists should consider evaluating possible systemic disorders in patients presenting with burning mouth symptoms without clinical lesions, to enable precise diagnosis and achieve optimal treatment outcomes.
References
Dworkin SF, Burgess JA. Orofacial pain of psychogenic origin: current concepts and classification. J Am Dent Assoc. 1987;115(4):565–71.
López-Jornet P, Camacho-Alonso F, Andujar-Mateos P, Sánchez-Siles M, Gómez-Garcia F. Burning mouth syndrome: an update. Med Oral Patol Oral Cir Bucal. 2010;15(4):562–8.
Klasser GD, Fischer DJ, Epstein JB. Burning mouth syndrome: recognition, understanding, and management. Oral Maxillofac Surg Clin North Am. 2008;20(2):255–71.
Scala A, Checchi L, Montevecchi M, Marini I, Giamberardino MA. Update on burning mouth syndrome: overview and patient management. Crit Rev Oral Biol Med. 2003;14(4):275–91.
Woda A, Dao T, Gremeau-Richard C. Pathophysiology of burning mouth syndrome: perspectives from pain research. J Orofac Pain. 2015;29(1):67–77.
Sharma N, Sharma A. Thyroid profile in menstrual disorders. JK Sci. 2012;14(1):14–17.
Guggenheimer J, Moore PA. The therapeutic applications of iron in oral medicine. Oral Dis. 2018;24(2):188–95.
Zakrzewska JM. Burning mouth syndrome. Oral Dis. 2021;27(4):829–43.
Grushka M, Sessle BJ, Howley TP. Psychophysical assessment of tactile, pain and thermal sensory functions in burning mouth syndrome. Pain. 1987;28(2):169–84.
Grushka M. Clinical features of burning mouth syndrome. Oral Surg Oral Med Oral Pathol. 1987;63(1):30–6.
Basker RM, Main DM. The cause and management of burning mouth condition. Spec Care Dentist. 1991;11(3):89–96.
Femiano F. Burning mouth syndrome (BMS): an open trial of comparative efficacy of alpha-lipoic acid (thioctic acid) therapy versus vitamin supplementation. J Oral Pathol Med. 2004;33(7):410–3.
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