Clinical Outcomes and Post-operative Complications Following Liver Resection for Hepatobiliary Tumors at Phetchabun Hospital

Abstract

Hepatobiliary tumors, which have high global incidence and are among the leading causes of cancer-related mortality, often require surgical resection as the mainstay of treatment, offering favorable clinical outcomes. This study aimed to describe the baseline clinical characteristics and tumor types and to evaluate the clinical outcomes and incidence of post-operative complications in patients undergoing hepatic resection in Phetchabun Hospital. This retrospective descriptive study included patients diagnosed with hepatobiliary tumors who underwent hepatic resection at the Department of Surgery, Phetchabun Hospital, between January 2017 and December 2022. Data were collected from electronic medical records and analyzed using standard statistical software. A total of 52 patients were included; 63.4% were male, with a median age of 59.5 years. The most common diagnosis was hepatocellular carcinoma (32.7%), followed by metastatic liver cancer (28.9%) and cholangiocarcinoma (19.2%). The median intraoperative blood loss and operative time were 200 milliliters and 270 minutes, respectively. The median length of hospital stay was 6.5 days. No postoperative mortality was reported. The most common complication was bile leakage, observed in 25 patients (48%), most were classified as grade A according to the International Study Group of Liver Surgery (ISGLS) criteria and resolved without the need for reoperation. In conclusion, hepatic resection at Phetchabun Hospital resulted in favorable clinical outcomes with no post-operative mortality. However, post-operative bile leakage, particularly grade A, was relatively common. Continuous improvement in surgical techniques to minimize this issue and vigilant monitoring for post-operative complications are recommended to further enhance patient outcomes.