Diagnostic accuracy of fine needle aspiration cytology for malignant detection In the Thyroid nodule at Maharat Nakhon Ratchasima Hospital
Keywords:
Thyroid nodules, cytology, fine needle aspiration, Maharat Nakhon Ratchasima hospitalAbstract
This study was survey research by Retrospective cross sectional diagnostic study method aimed to study the sensitivity, specificity, and accuracy of cytology results from fine needle aspiration, positive predictive value, negative predictive value by comparing with pathology results. and to study risk factors that cause thyroid cancer. The study was done in patients who had been diagnosed with thyroid nodules. that was aspirated with a small needle and had thyroid surgery In Maharat Nakhon Ratchasima Hospital from 1 January 2018 to 30 October 2021, data was analyzed by Sensitivity, specificity and diagnostic accuracy of Fine needle aspiration cytology, positive predictive value, negative predictive value was calculated by frequency, percentage and p-value by Chi square
Results : 188 patients, the mean age was 50 years old, and almost 95.2%—were women. 87% of patients with positive fine needle aspiration cytology results had cancer. Overall, the results revealed a sensitivity of 91.3% (P = 0.000), a specificity of 37% (P = 0.000), an accuracy rate of 64.29 % (P = 0.265), a positive predictive value of 45.6%, and a negative predictive value of 88%. Thyroid cancer risk factors consisted of symptoms such as lymphadenopathy of cervical lymph nodes and weight loss. The FNA cytology obtained using the ultrasonographic-guided FNA technique was significantly associated with increased thyroid cancer diagnostic accuracy.
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