Correlation between antenatal screening test and amniocentesis in diagnosis of congenital fetal anomalies in Dansai Crown Prince Hospital.

Abstract

     This is descriptive research aiming to identify on the relationship between fetal screening and amniocentesis in the diagnosis of congenital fetal abnormalities at Dansai crown prince hospital. Research objectives include:  the incidence of Q-Test screening tests being positive in pregnant women in Dansai, Phu Rua, and Na Haeo District ; the general characteristic and the obstetric history of pregnancy women, the results of the amniocentesis ; and to study the correlation between antenatal screening test and amniocentesis in diagnosis of congenital fetal anomalies. 247 pregnant women who undergone amniocentesis in Dansai crown prince hospital during the period June 2019 – 31^st August 2023. All of the study population was completed questionnaire about general characteristic including age, hospital providing, area of residence, the obstetric history about number of gravidity, number of parity and gestational age when Q-Test was performed, Q-Test results and fetal diagnosis results including chromosomes, AFP level, pregnancy termination and complications from amniocentesis. Data were analyzed using quantitative statistics including percentage, mean, standard deviation and correlation.

     The results of this study found that 4,192 pregnant women come to visit at antenatal care clinic at Dansai crown prince hospital in fiscal year 2019-2023. 198 pregnant women found positive Q-Test results, accounting for 4.72 percent. The study sample consisted of 247 pregnant women, most of them were in the age range of 35 -<40 years,47.4 percent, More than half of them lived in Dansai District (55.9 percent), 45.3 percent were the second gravidity and 53.8 percent were first parity, the gestational age when the Q-Test was done was mostly 15-15+6 weeks (45.7 percent). The chromosome test results were abnormal in 5 people (2.02 percent). No statistically significant at the 0.05 level in a correlation between the results of the Q-Test method and amniocentesis in terms of chromosomes and AFP level (r = 0.074, p = 0.245 and r = 0.068, p = 0.286).