FACTORS PREDICTING SURVIVAL OF CHOLANGIOCARCINOMA PATIENTS AFTER DIAGNOSED AND TREATMENT IN SISAKET HOSPITAL

Abstract

     This case-control study aimed to identify factors predicting survival in cholangiocarcinoma patients following diagnosis and treatment at Sisaket Hospital. The study involved 199 participants, categorized into two groups: 96 survivors and 103 deceased individuals. Data were collected via structured questionnaires between January 1, 2021, and October 30, 2023. Descriptive statistics, including frequency distributions, percentages, means, standard deviations, medians, the 25th percentile, and the 75th percentile, were employed to analyze the data. Predictive factors were assessed through multiple logistic regression, with results reported as adjusted odds ratios (AOR) and 95% confidence intervals (CI), and a significance level set at 0.05.
     The findings indicated that significant predictors of survival included marital status, disease stage, and cancer metastasis. Single patients had a 2.89-fold higher mortality risk than patients of other marital statuses (AOR=2.09, 95% CI=1.26-3.45). Those in stage 4 had a 4.23-fold higher mortality risk compared to patients in stages 1 to 3 (AOR=3.16, 95% CI=2.04-6.38). Furthermore, patients with metastasis had a 2.87-fold increased risk of mortality compared to non-metastatic cases (AOR=1.87, 95% CI=1.01-3.52). Other variables lacked sufficient data to confirm significant associations.