Factors associated with treat to target of gouty arthritis at King Narai Hospital.

Authors

  • Wuttirak Leelasattakul -

Keywords:

gout, treat-to-target

Abstract

     This study aimed to determine the factors associated with the targeted treatment of gouty arthritis, which recommends targeting serum uric acid levels <6 mg/dl. Methods: This study was survey research by collecting retrospective data of patients who were diagnosed with gouty arthritis, ICD-10 M100-109 code, who received treatment in the outpatient department at King Narai Hospital, Lopburi, between 1st January 2022 and 31st July 2025. The analysis examined the factors correlated with treat-to-target using multi-logistic regression and reported with odds ratio (OR) and 95% confidence interval (CI). A statistical significance level of p-value <0.05.

     Result: The Study samples were 146 patients. There was no significant difference in baseline characteristics between groups except for alcohol consumption. The factors associated with the treat-to-target of gouty arthritis were no alcohol consumption (adjusted OR 4.16, 95% CI 1.73-10.05, p 0.002) dosage of allopurinol > 100 mg/day (adjusted OR 2.22, 95% CI 1.04-4.73, p 0.40) and physicians specialties as internist (adjusted OR 2.16, 95% CI 1.02-4.55, p 0.043)

References

K. L. Wallace, A. A. Riedel, N.Joseph-Ridge and R.Wortmann. J Rheumatol 2004 Vol.31 Issue 8 Pages 1582-7.

R. C. Lawrence, C. G. Helmick, F. C. Arnett, R. A. Deyo, D. T. Felson, E. H. Giannini, et al. Arthritis Rheum 1998 Vol. 41 Issue 5 Pages 778-99.

T. R. Mikuls, J. T. Farrar, W. B. Bilker, S. Fernandes, H. R. Schumacher, Jr. and K. G. Saag. Ann Rheum Dis 2005 Vol. 64 Issue 2 Pages 267-72.

E. Krishnan, J. F. Baker, D.E. Furst and H. R. Schumacher. Arthritis Rheum 2006 Vol. 54 Issue 8 Pages 2688-96.

H. K. Choi and E. S. Ford. Am J Med 2007 Vol. 120 Issue 5 Pages 442-7.

H. K. Choi, M. A. De Vera and E. Krishnan. Rheumatology (Oxford) 2008 Vol. 47 Issue 10 Pages 1567-70.

Richette P, Bardin T. Gout. Lancet. 2010 Jan 23;375(9711):318-28.

Dalbeth N, Gosling AL, Gaffo A, Abhishek A. Gout. Lancet. 2021 May 15;397(10287):1843-55.

Deesomchoke U. Management of patients with joint diseases and rheumatism. Revised ed: Faculty of Medicine, Chulalongkorn University;2005.

J. D. FitzGerald, N. Dalbeth, T. Mikuls, R. Brignardello-Petersen, G. Guyatt, A. M. Abeles, et al. 2020 American College of Rheumatology Guideline for the Management of Gout. Arthritis Care Res (Hoboken) 2020 Vol. 72 Issue 6 Pages 744-760.

Saraswate CA, Brewer KK, Yang W, Patel PA, Schumacher HR, Saag KG, et al. Gout medication treatment patterns and adherence to standards of care from a managed care perspective. Mayo Clin Proc 2006

Jul; 81(7):925-34.

Singh JA, Hodges JS, Toscano JP, Asch SM. Quality of care for gout in the US needs improvement. Arthritis Rheum. 2007 Jun 15;57(5):822-9.

Chetanananda N. Drug Utilization review in patients with gouty arthritis at Takuatung Hospital. Med J Reg 11 2016;30: 115-28.

Hanvivadhanakul P, Wongdet R. Outcome of Treatment in Gouty Arthritis Patients: A Retrospective Study. J Med Assoc Thai. 2015 Apr;98 Suppl 3: S46-50.

Mangkala jintara. Treat-to-target of Gouty Arthritis at Rak-Kor Clinic Nongkhai Hospital. Journal of The Department of Medical Services 2022 Vol. 47 Issue 2 Pages 69-77.

L. N. Helget, A. Davis-Karim, J. R. O'Dell, T. R. Mikuls, J. A. Newcomb, M. Androsenko, et al. Am J Kidney Dis 2024 Vol. 84 Issue 5 Pages 538-545.

L. K. Stamp, W. J. Taylor, P. B. Jones, J. L. Dockerty, J. Drake, C. Frampton, et al. Arthritis Rheum 2012 Vol. 64 Issue 8 Pages 2529-36.

Janssen CA, Oude Voshaar MAH, Klooster PMT, Vonkeman HE, Laar MAFJ. Prognostic factors associated with early gout flare recurrence in patients initiating urate-lowering therapy during an acute gout flare Clin Rheumatol. 2019 Aug;38(8):2233-9.

S. H. Ralston, H. A. Capell and R. D. Sturrock. Br Med J (Clin Res Ed) 1988 Vol. 296 Issue 6637 Pages 1641-2.

Downloads

Published

2026-02-28

How to Cite

Leelasattakul, W. (2026). Factors associated with treat to target of gouty arthritis at King Narai Hospital. Journal of Environmental and Community Health, 11(1), 439–444. retrieved from https://he03.tci-thaijo.org/index.php/ech/article/view/5384