Impact Predictors of Chronic Kidney Disease in Diabetes Type 2 Patients, Udonthani Province

Abstract

     A cross-sectional analytical study this purpose aims to compare patient characteristics and clinical findings between treatments in 2018 and 2020, and factors predicting the effect on chronic kidney disease in T2DM patients, on July 2021, inclusion criteria were T2DM who received continuous treatment between 2018-2020 in hospitals under the Office of the Permanent Secretary, Ministry of Public Health in Udon Thani Province, both males and females aged 35-years old and had complete data according to the specified variables, totaling 11,646 patients. Research instruments using secondary data from electronic report of diabetic patients at 20 hospitals under the Udon Thani Provincial Public Health Office. Analyzed by using statistics such as frequency, percentage, mean, standard deviation, Paired-sample T-test, Multinomial Logistic regression, odds ratios (OR) and 95% Confidence Interval.

     The results indicated that the treatment outcomes between 2018 and 2020 were significantly different at <0.001, in descending order as follows: The treatment effect was improved, including HDL-cholesterol increase 36.3%, glomerular filtration increase 3.5%. The treatment outcome did not improve: waist circumference increases 2.4%, blood pressure level increase 0.6%, BMI increase 0.5%, cholesterol total increases 36.9%, FBS increase 10.3%, microalbuminuria increase 6.2%, LDL increase of 3.2%. The predictors of chronic kidney disease were 8 out of 13 risk factors at the 0.05 level were statistically significant. Overall predicted 2.08 times (OR 2.08, 95%CI: 1.01-1.40, p=<0.001). In descending order: BMI 1.19 times (OR 1.19), HbA1c 1.13 times (OR 1.13), Waist circumference 0.74 times (OR 0.74), Cholesterol total 0.55 times (OR 0.55), Associated disease 0.45 times (OR 0.45), Duration of type 2 diabetes 0.40 times (OR 0.40), age 0.24 times (OR 0.24), and Serum-creatinine 0.17 times (OR 0.17).