VACCINATION IN PRETERM INFANTS: CHALLENGE ROLES FOR NURSES

Authors

  • Usanee Jintrawet School of Nursing, Panyapiwat Institute of Management
  • Kaitsara Sen-Ngam School of Nursing, Panyapiwat Institute of Management
  • Tassaneeya Wangsachantanon School of Nursing, Panyapiwat Institute of Management
  • Chirakun Khrobsorn School of Nursing, Panyapiwat Institute of Management
  • Rungnobphanan Buppa School of Nursing, Panyapiwat Institute of Management
  • Chotika Channongwaeng School of Nursing, Panyapiwat Institute of Management

Keywords:

Immunization, Preterm Infants, Low Birth Weight Infants, Health Education, Nurse

Abstract

Preterm infants are at high risk of infection due to dysfunctional of immune system. So, postnatal vaccination at chronological age is important to their health. Based on reviewing of the literature, the issue of non-compliance to expanded program on immunization (EPI) was found, either earlier or later than the EPI. It is a challenge for nurses to have preterm infants meet the EPI. This article presents the meaning and the incidence of premature infants, factors related to premature birth, immune system of premature infants, the meaning and type of vaccine, how should premature infants receive vaccination, the studies related to vaccination in premature infants, vaccination in premature infants, and roles of nurses in providing knowledge to caregivers of premature infants. Health education by nurses with the participation of caregivers may help increase the number of receiving immunization among preterm infants.

References

Aisyah, H. I., & Tangpukdee, J. (2023). The effect of education intervention on caregiver’s knowledge about vaccination in children aged 0-23 months. Asia-Pacifc Journal of Science and Technology, 28(1), 1-8. https://doi.org/10/14456/apst.2023.4

American Academy of Pediatrics. (2018). Red book (2018): Report of the committee on infectious diseases (31st ed.). https://publications.aap.org/aapbooks/book/546/Red-Book-2018-Report-of-the-Committee-on

Angelidou, A. (2020). Vaccination of term and preterm infants. NeoReviews, 21(12), e817-e827. https://doi.org/10.1542/neo.21-12-e817

Bary-Weisberg, D., & Stein-Zamir, C. (2021). Vaccination timeliness and completeness among preterm and low birthweight infants: A national cohort study. Human Vaccines & Immunotherapeutics, 17(6), 1666-1674. https://doi.org/10.1080/21645515.2020.1840255

Cherayil, B. J., & Jain, N. (2024). From womb to world: Exploring the immunological connections between mother and child. ImmunoHorizon, 8, 552-562.

Chokephaibulkit, K., Lapphra, K., Techasaensiri, C., Tangsathapornpong, A., & Samkoses, R. (2019). Vaccine and immunization guide 2019. Printing Company Limited. [in Thai]

Collins, A., Weitkamp, J. - H., & Wynn, J. L. (2018). Why are newborns at increased risk of infection? Archives of Disease in Childhood and Fetal and Neonatal Edition, 103(4), F391-F394. https://doi.org/10.1136/archdischild-2017-313595

Crawford, N. W., & Buttery, J. P. (2010). Preterm infants immunization. Paediatrics and Child Health, 20(6), 297-301. https://doi.org/10.1016/j.paed.2010.02.011

Curran, A. (2025). Premature baby nursing diagnosis & care plan. https://nursestudy.net/premature-baby-nursing-diagnosis/

Department of Health, Ministry of Public Health. (2023). Situation of premature birth and operations to prevent premature birth in Health Region 7. https://hpci.anamai.moph.go.th>kpr>report66 [in Thai]

Division of Vaccine Preventable Diseases, Department of Disease Control, Ministry of Public Health. (2020). Expanded program on immunization the year 2563. https://ddc.moph.go.th/uploads/fles/1048320191202064105.pdf [in Thai]

Eunice Kennedy Shriver National Institute of Child Health and Human Development. (2023). What are the riskà factors for preterm labor and birth? https://www.nichd.nih.gov/health/topics/preterm/conditioninfo/who_risk

Fortmann, M. I., Dirks, J., Goedicke-Fritz, S., Leise, J., Zemlin, M., Morbach, H., & Härtel, C. (2022). Immunization of preterm infants: Current evidence and future strategies to individualized approach. Seminars in Immunopathology, 44, 767-784. https://doi.org/10.1007/s00281-022-00957-1

Gagneur, A., Pinquier, D., & Quach, C. (2015). Immunization of preterm infants. Human Vaccines & Immunotherapeutics, 11(11), 2556-2563.

Goenka, A., & Kollmann, T. R. (2015). Development of immunity in early life. Journal of Infection, 71, S112-S120.

Helmenstine, A. (2024). Active vs passive immunity-defnition and differences. https://sciencenotes.org/active-vs-passive-immunity-defnition-and-differences/

Helmo, F. R., Alves, E. A. R., de Andrade Moreira, R. A., Severino, V. O., Rocha, L. P., dos Reis Monteiro, M. L. G., dos Reis, M. A., Etchebehere, R. M., Machado, J. R., & Correa, R. R. M. (2018). Intrauterine infection, immune system and premature birth. The Journal of Maternal-fetal & Neonatal Medicine, 31(9), 1227-1233. https://doi.org/10.1080/14767058.2017.1311318

Janagaraj, P. D., Gurusamy, P. S. R., & Webby, R. (2018). Current antenatal pertussis vaccination guidelines miss preterm infants: An epidemiological study from the Northern Territory. Australian and New Zealand Journal of Obstetrics and Gynecology, 59(3), 436-443. https://doi.org/10.1111/ajo.12896

Khandre, V., Potdar, J., & Keerti, A. (2022). Preterm birth: An overview. Cureus, 14(12), e33006. https://doi.org/10.7759/cureus.3306

Lokossou, G. A. G., Kouakanou, L., Schumacher, A., & Zenclussen, A. C. (2022). Human breast mlk: From food to active immune response with disease protection in infants and mothers. Frontiers in Immunology, 5(13), 849012. https://doi.org/10.3389/fmmu.2022.849012

Martinelli, D., Fortunato, F., Matto, G. D., Iannelli, G., & Prato, R. (2020). Post-marketing surveillance study of DTaP2-IPV-HB-Hib (Hexyon) vaccine administered in preterm infants in the Apulia region, Italy, in 2017. Vaccine, 38, 5148-5153. https://doi.org/10.1016/j.vaccine.2020.06.033

Murki, S., Vardhelli, V., Dehabhotla, S., Sharma, D., Pawale, D., Kulkarni, D., Kumar, P., Kabra, N. S., Sundaram, M., Plakkal, N., Mehta, A., Tandur, B., Chawla, D., Sreeram, S., Saha, B., Rao, P. N. S., & Kadam, S. (2020). Predictors of length of hospital stay among preterm infants admitted to neonatal intensive care unit: Data from a multicentre collaborative network from India (INNC: Indian National Neonatal Collaborative). Journal of Paediatrics and Child Health, 56(10), 1584-1589. https://doi.org/10.1111/jpc.15031

Rouers, E. D. M., Berbers, G. A. M., van Dongen, J. A. P., Sanders, E. A. M., & Bruijning-Verhagen, P. (2019). Timeliness of immunizations in preterm infants in the Netherlands. Vaccine, 37(39), 5862-5867. https://doi.org/10.1016/j.vaccine.2019.08.006

Sioriki, A. A., Gkentzi, D., Papadimitriou, E., Dimitriou, G., & Karatza, A. (2020). Vaccinations in infants born preterm: An update. Current Pediatric Reviews, 16(2), 148-155. https://doi.org/10.2174/1573396316666200116094459

Slifka, M. K., & Amanna, I. J. (2018). Passive immunization. In Plotkin’s vaccines (pp. 84-95). Elsevier. https://doi.org/10.1016/B978-0-323-35761-6.00008-0

Soans, S., Mihalyi, A., Berlaimont, V., Kolhapure, S., Dash, R., & Agrawal, A. (2022). Vaccination in preterm and low birth weight infants in India. Human Vaccines & Immunotherapeutics, 18(1), 1-12. https://doi.org/10.1080/21645515.2020.1866950

Tangsthapornpong, A. (n.d.). General principles in vaccination. Chrome-extension://efaidnbmnnnibpcajpcglclefndmkaj/https://pidst.or.th/userfles/5_หลักการทั่วไปในการให้วัคซีน.pdf [in Thai]

Tooke, L., & Louw, B. (2019). A successful pretern vaccination program in a neonatal unit in a developing country. Heliyon, 5(11), e02857. https://doi.org/10.1016/j.heliyon.2019.e02857

Visscher, M. O., Carr, A. N., & Narendran, V. (2022). Epidermal immunity and function: Origin in neonatal skin. Frontiers in Molecular Biosciences, 9, 894496. https://doi.org/10.3389/fmolb.2022.894496

Wagner, M. (2025). Knowledge defcit nursing diagnosis & care plans. https://www.nursetogether.com/knowledge-defcit-nursing-diagnosis-care-plan/

Wilck, M. B., Xu, Z. L., Stek, J. E., & Lee, A. W. (2021). Safety and immunogenicity of a fullyliquid DTaP-IPV-Hib-HepB vaccine (VaxelisTM) in premature infants. Human Vaccines & Immunotherapeutics, 17(1), 191-196. https://doi.org/10.1080/21645515.2020.1756668

Wilde, B. B., & Park, D. J. (2019). Immunizations. Primary Care Clinics in Offce Practice, 46(1), 53-68. World Health Organization. (2023). Preterm birth. https://www.who.int/news-room/fact-sheets/detail/preterm-birth

Xu, Y., Ji, C., Liu, Y., Li, M., Yao, D., Wang, X., Du, J., & Chen, J. (2020). Vaccination recommendations, immunization status and safety of vaccination for premature infants in Zhejiang, China. Expert Review of Vaccines, 19(10), 973-981. https://doi.org/10.1080/14760584.2020.1831917

Zimmermann, P., & Jones, C. E. (2021). Factors that influence infant immunity and vaccine responses. The Pediatric Infectious Disease Journal, 1(40), S40-S46. https://doi.org/10.1097/INF.0000000000002773

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Published

30-06-2025

How to Cite

Jintrawet, U., Sen-Ngam, K., Wangsachantanon, T., Khrobsorn, C., Buppa, R., & Channongwaeng, C. (2025). VACCINATION IN PRETERM INFANTS: CHALLENGE ROLES FOR NURSES. Journal of Health and Food Creation, 3(1), 46–57. retrieved from https://he03.tci-thaijo.org/index.php/JHFC/article/view/4114

Issue

Vol. 3 No. 1 (2025): January - June 2025

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Articles

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