Nursing Care for Patients with Relapsed Schizophrenia Associated with Substance Use: A Comparative Case Study

Main Article Content

สมัย

Abstract

Schizophrenia with comorbid substance use is a major factor contributing to relapse. This study aimed to analyze associated factors, nursing problems, and care outcomes using a comparative case study design in two patients at Sriratana Hospital. Participants were selected using purposive sampling. Data were collected from retrospective medical records in 2025, in-depth interviews, and health assessments conducted between March 17 and April 30, 2026. Data were analyzed using content analysis based on Gordon’s Functional Health Patterns.


The findings revealed that both patients shared common factors, including lack of insight, poor medication adherence, and repeated substance use, which were associated with relapse. Patients who received adequate family support and continuous follow-up demonstrated significant reductions in psychiatric symptoms and relapse rates.


The study led to the development of the “Sriratana Relapse Prevention Guideline” and highlights that holistic nursing care combined with continuous family and community support plays a crucial role in preventing relapse.

Article Details

How to Cite
สมัย. (2026). Nursing Care for Patients with Relapsed Schizophrenia Associated with Substance Use: A Comparative Case Study. Sisaket Journal of Research and Health development, 5(2), p. 246–254. retrieved from https://he03.tci-thaijo.org/index.php/SJRH/article/view/5534
Section
Case study

References

กรมสุขภาพจิต. (2563). แนวทางการดูแลผู้ป่วยจิตเวชในชุมชน. กระทรวงสาธารณสุข.

กรมสุขภาพจิต. (2564). รายงานสถานการณ์สุขภาพจิตประเทศไทย ปีงบประมาณ 2564. กระทรวงสาธารณสุข.

จุฑามาศ ศรีสุวรรณ, และคณะ. (2564). ความสัมพันธ์ระหว่างการรับประทานยากับการกลับเป็นซ้ำในผู้ป่วยจิตเภท.

วารสารการพยาบาลจิตเวชและสุขภาพจิต, 35(2), 45–58.

ธนพร อินทร์สุข, และคณะ. (2563). ปัจจัยที่มีผลต่อการใช้สารเสพติดซ้ำในผู้ป่วยจิตเวช. วารสารสาธารณสุขและการพัฒนา,

(1), 75–89.

นงลักษณ์ สุขสม, และคณะ. (2565). บทบาทของครอบครัวในการดูแลผู้ป่วยจิตเภทในชุมชน. วารสารพยาบาลสาธารณสุข,

(1), 12–25.

American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.).

American Psychiatric Publishing.

Dixon, L. B., Holoshitz, Y., & Nossel, I. (2016). Treatment engagement of individuals experiencing mental

illness: Review and update. World Psychiatry, 15(1), 13–20. https://doi.org/10.1002/wps.20310

Gordon, M. (1994). Nursing diagnosis: Process and application (3rd ed.). Mosby.

Higashi, K., Medic, G., Littlewood, K. J., Diez, T., Granström, O., & De Hert, M. (2013). Medication adherence in

schizophrenia: Factors influencing adherence and consequences of nonadherence. Patient

Preference and Adherence, 7, 117–130. https://doi.org/10.2147/PPA.S39386

Hunt, G. E., Large, M. M., Cleary, M., Lai, H. M. X., & Saunders, J. B. (2018). Prevalence of comorbid substance

use in schizophrenia: A systematic review and meta-analysis. Addiction, 113(4), 660–669.

https://doi.org/10.1111/add.14079

Lincoln, T. M., Lüllmann, E., & Rief, W. (2007). Correlates and long-term consequences of poor insight in

patients with schizophrenia. Schizophrenia Bulletin, 33(6), 1324–1342.

https://doi.org/10.1093/schbul/sbm002

Mueser, K. T., Noordsy, D. L., Drake, R. E., & Fox, L. (2000). Integrated treatment for dual disorders: A guide

to effective practice. Guilford Press.

Pharoah, F., Mari, J. J., Rathbone, J., & Wong, W. (2010). Family intervention for schizophrenia. Cochrane

Database of Systematic Reviews, (12), CD000088. https://doi.org/10.1002/14651858.CD000088.pub3

Townsend, M. C. (2015). Psychiatric nursing: Concepts of care (8th ed.). F. A. Davis.

World Health Organization. (2021). Guidance on community mental health services: Promoting person-

centred and rights-based approaches. https://www.who.int