Situation and Diagnostic of Leptospirosis in Khukhan Hospital, Srisaket province since October 2019 to 2023
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Abstract
Leptospirosis is considered a disease that is a public health problem in Thailand. It is an animal disease that can be transmitted to people. The incidence of the disease is found to be high in countries with tropical climates. Thailand found patients across all regions of the country, but most commonly in the southern and northeastern regions. Sisaket Province had a higher disease incidence rate than the national. This study aims to study the epidemiological situation of leptospirosis in patients receiving treatment at Khukhan Hospital and to confirm the diagnosis of leptospirosis in patients admitted to Khukhan Hospital, between October 2019 and October 2023, data were collected using data recording forms and laboratory data, confirmation were tested using real-time PCR and microscopic agglutination test (MAT) methods. Differences were analyzed using the Mann-Whitney U test, mean, median, and compare mean t-test.
The results found that are several patients 98 cases of suspected leptospirosis were examined to confirm the genetic diagnosis of leptospirosis. It was found that they were not infected with leptospirosis, 47 cases, 47.96 percent, most of whom were infected with leptospirosis, 51 cases, 52.04 percent. Most infected people had severe symptoms, 31 cases, 60.78 percent and mild symptoms 20 cases, 39.22 percent. In which 2 infected people with severe symptoms died, they were males, ages 66 and 68, and had a SOFA score of more than 2 that assesses the function of the blood system, Kidney function and liver function, In which infection was detected in both blood and urine 1 case, 50.00 percent, and infection was found only in the blood 1 case, 50.00 percent.
Conclusion of study results Leptospirosis is found in more than half of patients, from the results of the diagnosis of Leptospirosis disease fast and accurate leptospirosis It is very necessary to provide guidelines for the timely treatment of patients with leptospirosis.
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เนื้อหาและข้อมูล (เขียนข้อกำหนด)
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