Influence factors for Re-Infection Opisthrochis viverini in Sisaket Province and Effectiveness of E-Bookincrease knowledge and attitude to prevent Opisthrochis viverini Infection to

Abstract

This  study was  a  research  and  development  ( R&D ) study   aimed  to  investigate  factors  rerated  to  reinfection  liver  fluke  among  people  in  Sisaket  Province and  study  effective of  E-Book  to  increase knowledge  attitudes and behaviors to  prevent  liver  fluke . The  sample  . Consisted  of  people  who  tested  parasite  examination  found  a liver  fluke  during 2017-2021 in  Sisaket  Provence. Classified  as  twice  or  more   reinfection 127  case  and  control 254 case  didn’t  reinfection  in  the  same  time.  Interview  were  used  to collected  data by  interview  two target  group. Analyze  data  by  simple logistic  regression and multivariable  logistic  regression. Crude  odds  ratio (OR_c) , Adjusted  odds  ratio(OR_A)  and  95 % Confidence  Interval  were  presented.The  result  found  the  statistically  significant  factors  related  to the re-infection  liver  fluke  included  income of the family  less  than 5,000 Baht (OR_A = 2.06 , 95 % CI = 1.12 -3.80  p-value = 0.0201)  and  disease  prevention  practice  (OR_A = 0.60 , 95 % CI = 0.36-0.98  p-value = 0.0418). The effectiveness of using E-Book in increasing knowledge and attitude in preventing liver fluke disease. Compared before and after the experiment using Paired T-test statistics.The  result  of  E-Book effective  to  increase knowledge  and  attitude  found  by paired T-test statistically significant increase  knowledge  ( p-value < 0.0001 , 95  % CI =2.70-4.20 )  and  increase  Attitude  to recognition benefit  of  prevented  disease ( p-value = 0.0001 , 95  % CI =1.03-2.81).From  result  of the  study , Health  personal  must  speed  up  to  increase  disease  prevention  practice  among  people  in  Sisaket  Province  and  use  E-Book  to  educate  people   to  reduse  liver  fluke  infection   that  cause  of  died  with Cholangiocarcinoma   as well as  a compainge  to eat  cooked  picklet  fish  to  reduce  the liver  fluke infection  rate  and incident  of Cholangiocarcinoma.